Unlike all other cell types in our brain, microglial cells are not differentiated from neural stem cells (Yang et al., 2013); they derive from myeloid  Cognitine progenitor cells migrating through the blood vessels (Harry, 2013). By migrating along radial glial cells, white matter tracts, and the vasculature (Rezaie and Male, 1999), microglial cells reach the ventricular zone by week 6, extent into the marginal zone by week 8, and spread into the subventricular zone, the intermediate zone, and the subplate around week 16 (Raybaud et al., 2013). As neurons become Cognitine Review established in the brain, the need to clear excess neurons is reduced, and microglial cells undergo a morphological transition from amoeboid to heavily branched (Monier et al., 2006). By week 35, the cells display a fully developed, ramified morphology (Esiri et al., 1991).

http://www.supplementsoffer.com/cognitine-review

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